Research News

Writer: Dr. Ruiyang Ge @ University of British Columbia 22q11.2 deletion syndrome (22q11DS) stands as the most prevalent microdeletion in humans. This genetic condition is linked to notable effects on brain structure, marked by substantial reductions in gray matter volume. Additionally, it manifests in neuropsychiatric symptoms, encompassing cognitive impairment and psychosis. The ENIGMA 22q11.2 Deletion Syndrome Working Group has recently shared a publication entitled "Sourc

Writer: Dr. Shalaila Haas @ ISMMS This study was the first application of the robust and large scale normative models developed by Ge and colleagues to a clinical sample. Normative modeling provides standards or "norms" at different ages for specific measures. In this case, normative models were generated for each region in the brain in more than 37,000 healthy individuals. These models can then be applied to other datasets, for example patients with a specific mental illness

Writer: Dr. Ruiyang Ge @ University of British Columbia In the last two decades, neuroimaging techniques have become essential tools for both basic research and clinical studies of the human brain. However, there is currently a lack of reference standards to accurately quantify individual differences in neuroimaging metrics across the human lifespan. Normative values are a common tool in psychology and medicine to assess individual risk and aid in diagnosis at the level of a